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Precision Medicine Group

Remote, United States

Posted on: 26 January 2026

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Manager End User Computing

The Manager of End User Compute Services is a collaborative leader and go-getter responsible for the global strategy and optimization of the Microsoft 365 ecosystem (O365, Intune, Entra ID), Mac management (Jamf), and VDI environments. This role requires a high-energy individual who blends deep technical execution with people management to deliver a secure, automated, and seamless digital workplace. You will work hand-in-hand with SecOps, HR and BRM to drive zero-touch automation across the entire employee lifecycle.

Main Duties & Responsibilities • Collaborative Leadership: Lead and mentor a global team of engineers to deliver high-performing identity and endpoint services. • M365 Mastery: Administer and optimize the Microsoft 365 tenant, including Exchange Online, SharePoint, OneDrive, Teams, and associated collaboration tools. • Security Partnership: Work closely with SecOps to implement Zero Trust principles, Conditional Access, and Defender integration. • Automation & Lifecycle: Design and deploy end-to-end employee lifecycle automations integrated with HRIS systems (Workday, etc) to ensure seamless onboarding/offboarding. • Unified Endpoint Management: Oversee operations for Intune and Microsoft Configuration Manager (MECM) while providing expert-level management of Apple Mac environments via Jamf. • VDI Management: Lead the strategy and delivery of virtual desktop solutions (Azure Virtual Desktop/Windows 365) to support a global, flexible workforce. • Governance: Drive license optimization, patch compliance, and consistent hardware/software configurations across Windows and macOS. • Operational Excellence: Define and track KPIs/SLAs while acting as a high-level technical escalation point for complex incidents and ensure root-cause resolution for recurring issues. • Develop technical documentation, SOPs, and tra

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manager
design
hr
security
technical
support
microsoft
leader
strategy
management
lead
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digital nomad
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